Notes: Bacteriophage

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* Definition: obligate intracellular parasites that multiply inside bacteria by making use of some or all of the host biosynthetic machinery.

* Significance

-Models for animal cell viruses

Gene transfer in bacteria

- Medical applications

- Identification of bacteria - phage typing

- Treatment and prophylaxsis ???



WHAT ARE BACTERIOPHAGES?

Viruses that attack bacteria were observed by Twort and d'Herelle in 1915 and 1917.

They observed that broth cultures of certain intestinal bacteria could be dissolved by addition of a bacteria -free filtrate obtained from sewage.


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